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Upon pickup, Transforms all Strikes and Defends. See the Transform page for more details.

Pandora's Box is a Boss Relic. It must be unlocked with the Silent's 4th unlock.

This relic will not spawn if any of the following run modifiers are used: Draft, Sealed Deck, Insanity, or Shiny.

Interactions[]

Update History[]

  • Weekly Patch 53: Blizzard
    • Crash fix when looking at Deck, Map, or Settings after getting Pandora's Box at Neow.
  • Weekly Patch 52: Release Date Price Increase
    • Updated relic asset for Pandora's Box.
    • Fixed issue where Pandora's Box relic couldn't transform cards to Rare.
  • Weekly Patch 50: The Final Act
    • Daily mods that alter the starting deck like Sealed Deck and Draft now eliminate Pandora's Box as it does nothing.
  • Weekly Pact 48: Creative AI
    • Added logic to remove the Strike tip from Pandora's box (attempt 2).
  • Weekly Patch 33: Terror
    • Obtaining Pandora's Box without Strikes or Defends no longer opens a blank screen.
  • Weekly Patch 25: Building Blocks
    • Game now saves after receiving cards from Pandora's Box and Astrolabe via Neow so your cards don't vanish.
  • Weekly Patch 21: Channel Lightning
    • Adding apostrophe to Pandora's Box.
  • Weekly Patch 20: Immolate
    • Potential fix for Pandora's Box and Calling Bell issues and exploits.
    • Typo fix in Pandora's Box helper text.
  • Weekly Patch 19: Seed
    • Potential fix for Calling Bell and Pandora's Box edge case issues.
  • Weekly Patch 18: Paranormal
    • Fix for Calling Bell/Library/Pandora's Box exploit.
Relics
Starter

BurningBloodRingoftheSnakeCrackedCorePureWater-0

Common

AkabekoAnchorAncientTeaSetArtofWarBagofMarblesBagofPreparationBloodVialBronzeScalesCentennialPuzzleCeramicFishDamaruDataDiskDreamCatcherHappyFlowerJuzuBraceletLanternMawBankMealTicketNunchakuOddlySmoothStoneOmamoriOrichalcumPenNibPotionBeltPreservedInsectRedSkullRegalPillowSmilingMaskSnakeSkullStrawberryBootTinyChestToyOrnithopterVajraWarPaintWhetstone

Uncommon

BlueCandleBottledFlameBottledLightningBottledTornadoDarkstonePeriaptYang-0EternalFeatherFrozenEgg2CablesGremlinHornHorn cleatInkBottleKunaiLetterOpenerMatryoshkaMeatontheBoneMercuryHourglassMoltenEgg2MummifiedHandNinjaScrollOrnamentalFanPantographPaperCranePaperFrogPearQuestionCardSelfFormingClayShurikenSingingBowlStrikeDummySundialSymbioticVirusTear drop locketTheCourierToxicEgg2WhiteBeastStatue

Rare

BirdFacedUrnCalipersCaptain wheelChampionBeltCharonsAshesCloakClaspDeadBranchDu-VuDollEmotionChipFossilizedHelixGamblingChipGingerGiryaGolden eyeIceCreamIncenseBurnerLizardTailMagicFlowerMangoOldCoinPeacePipePocketwatchPrayerWheelShovelStoneCalendarTheSpecimenThreadandNeedleTingshaToriiToughBandagesTungstenRodTurnipUnceasingTopWingedGreaves

Boss

AstrolabeBlackBloodBlackStarBustedCrownCallingBellCoffeeDripperCursedKeyEctoplasmEmptyCageFrozenCoreFusionHammerHoly waterHoveringKiteInserterMarkofPainNuclearBatteryPandorasBoxPhilosophersStoneRingoftheSerpentRunicCubeRunicDomeRunicPyramidSacredBarkSlaversCollarSneckoEyeSozuTinyHouseVelvetChokerViolet lotusWristBlade

Event

BloodyIdolCultistMaskEnchiridionFaceOfClericGoldenIdolGremlinMaskMarkoftheBloomMutagenicStrengthNlothsGiftNlothsMaskNecronomiconNeowsBlessingNilrysCodexOddMushroomRedMaskSpiritPoopSsserpentHeadWarpedTongs

Shop

BrimstoneCauldronChemicalXClockworkSouvenirDollysMirrorFrozenEyeHandDrillLeesWaffleMedicalKitMelangeMembershipCardOrangePelletsOrreryPrismaticShardRunicCapacitorSlingStrangeSpoonTheAbacusToolboxTwistedFunnel

Special

Circlet

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